Differential haplotypic expression of the interleukin-18 gene
نویسندگان
چکیده
منابع مشابه
Evaluation of Grapefruit Juice in terms of Interleukin 18 Gene Expression in Rats with Fatty Liver and Healthy Rats
Introduction: Interleukin 18 (IL-18) is a member of the cytokine family and an important regulator of inflammatory reactions. Due to the severe and irreversible complications of this disease in the advanced stages, timely treatment, especially with herbal medicines, can be considered an important strategy. This study aimed to investigate the effect of grapefruit extract on the IL-18 gene expres...
متن کاملMolecular Basis of Differential Gene Expression in Themouse Preimplantation Embryo
Preimplantation development of the mammalian embryo consists of stages that include formation of the <span style="font-variant: normal; font-style: normal; font-family: ArialM...
متن کاملInterleukin-18 expression in cystic fibrosis lungs.
susceptible populations to environmental exposures, we are developing a gene expression database for a rat cardiopulmonary disease model exposed to air pollutants. The spontaneously hypertensive (SH) rat with underlying cardiovascular and pulmonary disease risk is being utilized toward these efforts. SH rats with polygenic traits toward hypertension exhibit similar heritable risk factors that a...
متن کاملGenetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease.
BACKGROUND Interleukin (IL)-18 plays a key role in atherosclerosis and its complications. The present study investigated the genetic variability of 4 genes of the IL-18 system-IL18, IL18R1, IL18RAP, and IL18BP-in relation to circulating IL-18 levels and cardiovascular mortality. METHODS AND RESULTS Twenty-two polymorphisms were genotyped in 1288 patients with coronary artery disease prospecti...
متن کاملDifferential expression of the GTL2 gene within the callipyge region of ovine chromosome 18.
The inheritance pattern of the skeletal muscle hypertrophy phenotype caused by the callipyge gene has been characterized as polar overdominance. We hypothesized that this trait may be caused by a gain or loss of gene expression because of the reversible nature of the phenotype in paternal vs. maternal inheritance. Suppression subtraction cDNA probes were made from skeletal muscle mRNA of normal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 2007
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5201842